Next-Generation GxP Architecture

The Connected Quality Platform for Life Sciences

One unified quality layer across 8 core modules with built-in ALCOA+ cryptographic data integrity.

Document Management

Automated GxP document lifecycle with 21 CFR Part 11 electronic signatures, controlled copy watermarks, and cryptographic source file hashing.

FDA 21 CFR Part 11 • Annex 11 • ISO 13485
Module Blueprint

Quality Events & CAPA

Structured intake for 7 event types (Incidents, Deviations, Complaints, OOS/OOT) with guided 5-Whys RCA, auto-CAPA triggers, and effectiveness checks.

FDA QMSR (21 CFR 820) / ISO 13485 §8.5 • 21 CFR 211.192
Module Blueprint

Change Control

Govern process, equipment, and IT changes with mandatory multi-disciplinary impact assessments and risk-based CCB approval routing.

FDA QMSR (21 CFR 820) / ISO 13485 §7.3 • ICH Q10 • Annex 15
Module Blueprint

Training Management

Snapshot-locked quiz integrity, automated SOP training triggers upon document release, and expirable qualification matrices.

FDA QMSR / ISO 13485 §6.2 • 21 CFR 211.25
Module Blueprint

Risk Management

Central dynamic FMEA engine with severity dominance, statistical drift alerts, ALARP justifications, and direct cross-module traceability.

ISO 14971:2019 • ICH Q9 (R1) • ISO 13485 §7.1
Module Blueprint

Audit Management

End-to-end planning, execution, and reporting for internal, supplier, and regulatory audits with the Unified Assignment Framework.

ISO 19011:2018 • FDA QMSR / ISO 13485 §8.2.4
Module Blueprint

Supplier Quality

Approved Supplier Lists, automated certificate renewal alerts, quality hold suspensions, and zero-license external SCAR vendor portals.

FDA QMSR / ISO 13485 §7.4 • ICH Q7 & Q10 • 21 CFR 211.84
Module Blueprint

Command Center & Analytics

Real-time compliance scorecard, single-inbox My Work queue, management review packages, and cryptographic audit hash chain verification.

ISO 13485 §5.6 • ICH Q10 • ALCOA+ Integrity
Module Blueprint
Interactive Risk Engine Simulator

Dynamic ISO 14971:2019 / ICH Q9(R1) Risk Intelligence Core

See how QMSdesk automatically detects risk drift and auto-triggers CAPA workflows upon critical threshold breach.

Real-time Logic Active
Severity (Harm Impact)Level 4/5 (Major)
1 - Negligible2 - Minor3 - Moderate4 - Critical5 - Catastrophic
Occurrence LikelihoodLevel 3/5
1 - Improbable2 - Remote3 - Occasional4 - Probable5 - Frequent
Detection DifficultyLevel 2/5
1 - Almost Certain Detection3 - Moderate Detection5 - Undetectable

5x5 Risk Heatmap Coordinate

S5P1
S5P2
S5P3
S5P4
S5P5
S4P1
S4P2
S4P3
S4P4
S4P5
S3P1
S3P2
S3P3
S3P4
S3P5
S2P1
S2P2
S2P3
S2P4
S2P5
S1P1
S1P2
S1P3
S1P4
S1P5
Assessed Risk Status
HIGHRPN: 24
Raw Matrix4 × 3 = 12
Architectural Guardrails Applied:
  • ISO 14971 Hazard classification mapped automatically.
  • Cross-module traceability to SOPs, Audits, and Supplier records.
Automated Engine Response

⚠️ HIGH RISK: Flags 30-Day Cluster Alert and requires Quality Manager formal mitigation plan approval.

Automated GxP Document Lifecycle

Streamlined Document Lifecycle & Signature Workflow

Experience how QMSdesk simplifies compliance: from authoring to effective release in 5 intuitive, foolproof steps.

Regulatory Compliance21 CFR Part 11 & SoD Enforced
Stage 01 of 05STATE: DRAFT

Drafting & Authoring

Primary Role: Document Author (e.g. Lead Scientist / QC Analyst)
Required Workflow Actions:
  • Author SOP or Work Instruction in rich-text editor or upload DOCX template
  • Attach scope, department metadata, and target effective date
  • Define initial change justification and impacted job curricula
Automated GxP Safeguard

SHA-256 cryptographic file hashing on upload verifies zero byte-level corruption.

Automatic System Trigger

Auto-assigns unique document ID (e.g. SOP-QC-042-v1.0) and locks concurrent draft editing.

Want to test this in a live sandbox?Book 1-on-1 Document Workflow Walkthrough